Tranxene (Clorazepate) 7.5mg

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product. Buy Tranxene (Clorazepate) 7.5mg Online.

Tablet, Oral, as dipotassium:

Tranxene-T: 3.75 mg [DSC] [contains fd&c blue #2 (indigotine)]

Tranxene-T: 7.5 mg [contains fd&c yellow #6 (sunset yellow)]

Tranxene-T: 7.5 mg [DSC] [scored; contains fd&c yellow #6 (sunset yellow)]

Generic: 3.75 mg, 7.5 mg, 15 mg

Pharmacology

Mechanism of Action

Binds to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron at several sites within the central nervous system, including the limbic system and reticular formation. Enhancement of the inhibitory effect of GABA on neuronal excitability results by increased neuronal membrane permeability to chloride ions. This shift in chloride ions results in hyperpolarization (a less excitable state) and stabilization. Benzodiazepine receptors and effects appear to be linked to the GABA-A receptors. Benzodiazepines do not bind to GABA-B receptors (Nelson 1999). Buy Tranxene (Clorazepate) 7.5mg Online.